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DEDICATED TO EXCELLENCE IN CUSTOM SYNTHESIS Cal BioChemicals can be a value-creating partner for both established and start-up chemical companies by providing custom synthesis services.

New synthetic routes for known compounds
Synthesis of novel compounds
Scale-up (gram to kilogram quantities)
Chemical process development
Specialty chemicals

Chemical Reactions Can be performed at Cal BioChemicals (including but not limited to)

Acylation Grignard
Addition Halogenation
Alkylation Hydrogenation
Amination Hydrolysis
Arylation Column Content
Bromination Metal hydride
Chiral resolution Nitration
Condensation Nitrosation
Coupling Reactions Michaelis–Arbuzov
Cyanations Oxidation
Cyclization Organometallic
Decarboxylation Quaternization
Dehydration Reduction
Diazotization Rearrangement
Dieckmann Sulfonation
Diels-Alder Thioalkylation
Dehydrogenation Transesterification
Esterification Vilsmeier-Haack
Friedel-Crafts Von-Braun

Instrumentation

NMS Nuclear Magnetic Spectrometer 400MHz
NMS Nuclear Magnetic Spectrometer 500MHz
EPR Electron Paramagnetic Spectrometer -
FESEM Field Emission Scanning Electron Microscope
CRM-AFM Confocal Raman Microscope with AFM
AFM Atomic Force Microscope
FLIM Fluorescence-Lifetime Imaging Microscope
HRMS High Resolution Mass Spectrometer
LC-MS Liquid Chromatography-Mass Spectrometer
GC-MS Gas Chromatography-Mass Spectrometer
- Single Crystal X-Ray Diffractometer
- Single Crystal X-Ray Diffractometer (Microfocus source)
PXRD Powder X-ray Diffractometer
SWAXS Small and Wide Angle X-ray Scattering Diffractometer
HPLC High Performance Liquid Chromatography System
GC Gas Chromatography System
TGA-MS Thermograviemtric Analyzer - Mass Spectrometer
DSC Differential Scanning Calorimeter
DSC Differential Scanning Calorimeter for Liquid Samples
ITC Isothermal Titration Calorimeter
VIS UV-VIS Spectrometer
- Fluorimeter
CD Circular Dicrhroism Spectrometer
FTIR Fourier-Transform Infrared Spectrometer
- Femtosecond Fluorence Up-Conversion and Pump Probe Setup
- Nanosecond Laser Flash Photolysis System
CHNS Elemental Analyzer
- Spin Coater
- Dynamic Vapour Sorption Analyzer
- Dynamic Light Scattering System
- Polarimeter
- Hydrogenation Apparatus and Ozoniser
- Freeze Dryer
- BET Analyzer
- Photochemical Reactor
- Microwave Reactor